Interleukin-1β Attenuates Myofibroblast Formation and Extracellular Matrix Production in Dermal and Lung Fibroblasts Exposed to Transforming Growth Factor-β1

One of the most potent pro-fibrotic cytokines is transforming growth factor (TGFβ). TGFβ is involved in the activation of fibroblasts into myofibroblasts, resulting in the hallmark of fibrosis: the pathological accumulation of collagen. Interleukin-1β (IL1β) can influence the severity of fibrosis, h...

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Detalles Bibliográficos
Autores principales: Mia, Masum M., Boersema, Miriam, Bank, Ruud A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951452/
https://www.ncbi.nlm.nih.gov/pubmed/24622053
http://dx.doi.org/10.1371/journal.pone.0091559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951452/
https://www.ncbi.nlm.nih.gov/pubmed/24622053
http://dx.doi.org/10.1371/journal.pone.0091559

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