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Proteomics Analysis of Normal and Senescent NG108-15 Cells: GRP78 Plays a Negative Role in Cisplatin-Induced Senescence in the NG108-15 Cell Line

Accelerated senescence (ACS) leading to proliferative arrest is a physiological mechanism of the DNA damage response that occurs during tumor therapy. Our experiment was designed to detect unknown genes that may play important roles in cisplatin-induced senescence and to illustrate the related senes...

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Detalles Bibliográficos
Autores principales: Li, Wei, Wang, Wei, Li, Yan, Wang, Wenwen, Wang, Tian, Li, Li, Han, Zhiqiang, Wang, Shixuan, Ma, Ding, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951507/
https://www.ncbi.nlm.nih.gov/pubmed/24621580
http://dx.doi.org/10.1371/journal.pone.0090114