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Nitric Oxide-Induced Apoptosis of Human Dental Pulp Cells Is Mediated by the Mitochondria-Dependent Pathway

Nitric oxide (NO) is recognized as a mediator and regulator of inflammatory responses. NO is produced by nitric oxide synthase (NOS), and NOS is abundantly expressed in the human dental pulp cells (HDPCs). NO produced by NOS can be cytotoxic at higher concentrations to HDPCs. However, the mechanism...

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Detalles Bibliográficos
Autores principales: Park, Min Young, Jeong, Yeon Jin, Kang, Gi Chang, Kim, Mi-Hwa, Kim, Sun Hun, Chung, Hyun-Ju, Jung, Ji Yeon, Kim, Won Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951820/
https://www.ncbi.nlm.nih.gov/pubmed/24634593
http://dx.doi.org/10.4196/kjpp.2014.18.1.25