Targeting diseased tissues by pHLIP insertion at low cell surface pH

The discovery of the pH Low Insertion Peptides (pHLIPs®) provides an opportunity to develop imaging and drug delivery agents targeting extracellular acidity. Extracellular acidity is associated with many pathological states, such as those in cancer, ischemic stroke, neurotrauma, infection, laceratio...

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Detalles Bibliográficos
Autores principales: Andreev, Oleg A., Engelman, Donald M., Reshetnyak, Yana K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952044/
https://www.ncbi.nlm.nih.gov/pubmed/24659971
http://dx.doi.org/10.3389/fphys.2014.00097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952044/
https://www.ncbi.nlm.nih.gov/pubmed/24659971
http://dx.doi.org/10.3389/fphys.2014.00097

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