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A conservation and rigidity based method for detecting critical protein residues
BACKGROUND: Certain amino acids in proteins play a critical role in determining their structural stability and function. Examples include flexible regions such as hinges which allow domain motion, and highly conserved residues on functional interfaces which allow interactions with other proteins. De...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952096/ https://www.ncbi.nlm.nih.gov/pubmed/24565061 http://dx.doi.org/10.1186/1472-6807-13-S1-S6 |