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Assembly of Nsp1 Nucleoporins Provides Insight into Nuclear Pore Complex Gating

Nuclear pore complexes (NPCs) form gateways for material transfer across the nuclear envelope of eukaryotic cells. Disordered proteins, rich in phenylalanine-glycine repeat motifs (FG-nups), form the central transport channel. Understanding how nups are arranged in the interior of the NPC may explai...

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Detalles Bibliográficos
Autores principales: Gamini, Ramya, Han, Wei, Stone, John E., Schulten, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952814/
https://www.ncbi.nlm.nih.gov/pubmed/24626154
http://dx.doi.org/10.1371/journal.pcbi.1003488