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Assembly of Nsp1 Nucleoporins Provides Insight into Nuclear Pore Complex Gating
Nuclear pore complexes (NPCs) form gateways for material transfer across the nuclear envelope of eukaryotic cells. Disordered proteins, rich in phenylalanine-glycine repeat motifs (FG-nups), form the central transport channel. Understanding how nups are arranged in the interior of the NPC may explai...
Autores principales: | Gamini, Ramya, Han, Wei, Stone, John E., Schulten, Klaus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952814/ https://www.ncbi.nlm.nih.gov/pubmed/24626154 http://dx.doi.org/10.1371/journal.pcbi.1003488 |
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