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An In-Silico Model of Lipoprotein Metabolism and Kinetics for the Evaluation of Targets and Biomarkers in the Reverse Cholesterol Transport Pathway

High-density lipoprotein (HDL) is believed to play an important role in lowering cardiovascular disease (CVD) risk by mediating the process of reverse cholesterol transport (RCT). Via RCT, excess cholesterol from peripheral tissues is carried back to the liver and hence should lead to the reduction...

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Detalles Bibliográficos
Autores principales: Lu, James, Hübner, Katrin, Nanjee, M. Nazeem, Brinton, Eliot A., Mazer, Norman A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952822/
https://www.ncbi.nlm.nih.gov/pubmed/24625468
http://dx.doi.org/10.1371/journal.pcbi.1003509