DNA Dynamics during Early Double-Strand Break Processing Revealed by Non-Intrusive Imaging of Living Cells

Chromosome breakage is a major threat to genome integrity. The most accurate way to repair DNA double strand breaks (DSB) is homologous recombination (HR) with an intact copy of the broken locus. Mobility of the broken DNA has been seen to increase during the search for a donor copy. Observing chrom...

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Detalles Bibliográficos
Autores principales: Saad, Hicham, Gallardo, Franck, Dalvai, Mathieu, Tanguy-le-Gac, Nicolas, Lane, David, Bystricky, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952824/
https://www.ncbi.nlm.nih.gov/pubmed/24625580
http://dx.doi.org/10.1371/journal.pgen.1004187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952824/
https://www.ncbi.nlm.nih.gov/pubmed/24625580
http://dx.doi.org/10.1371/journal.pgen.1004187

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