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Alternate pleckstrin homology domain orientations regulate dynamin-catalyzed membrane fission
The self-assembling GTPase dynamin catalyzes endocytic vesicle scission via membrane insertion of its pleckstrin homology (PH) domain. However, the molecular mechanisms underlying PH domain–dependent membrane fission remain obscure. Membrane-curvature–sensing and membrane-curvature–generating proper...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952856/ https://www.ncbi.nlm.nih.gov/pubmed/24478459 http://dx.doi.org/10.1091/mbc.E13-09-0548 |