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Alternate pleckstrin homology domain orientations regulate dynamin-catalyzed membrane fission

The self-assembling GTPase dynamin catalyzes endocytic vesicle scission via membrane insertion of its pleckstrin homology (PH) domain. However, the molecular mechanisms underlying PH domain–dependent membrane fission remain obscure. Membrane-curvature–sensing and membrane-curvature–generating proper...

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Detalles Bibliográficos
Autores principales:	Mehrotra, Niharika, Nichols, Justin, Ramachandran, Rajesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952856/ https://www.ncbi.nlm.nih.gov/pubmed/24478459 http://dx.doi.org/10.1091/mbc.E13-09-0548

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