An H3K9/S10 methyl-phospho switch modulates Polycomb and Pol II binding at repressed genes during differentiation

Methylated histones H3K9 and H3K27 are canonical epigenetic silencing modifications in metazoan organisms, but the relationship between the two modifications has not been well characterized. H3K9me3 coexists with H3K27me3 in pluripotent and differentiated cells. However, we find that the functioning...

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Detalles Bibliográficos
Autores principales: Sabbattini, Pierangela, Sjoberg, Marcela, Nikic, Svetlana, Frangini, Alberto, Holmqvist, Per-Henrik, Kunowska, Natalia, Carroll, Tom, Brookes, Emily, Arthur, Simon J., Pombo, Ana, Dillon, Niall
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952858/
https://www.ncbi.nlm.nih.gov/pubmed/24430871
http://dx.doi.org/10.1091/mbc.E13-10-0628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952858/
https://www.ncbi.nlm.nih.gov/pubmed/24430871
http://dx.doi.org/10.1091/mbc.E13-10-0628

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