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An H3K9/S10 methyl-phospho switch modulates Polycomb and Pol II binding at repressed genes during differentiation
Methylated histones H3K9 and H3K27 are canonical epigenetic silencing modifications in metazoan organisms, but the relationship between the two modifications has not been well characterized. H3K9me3 coexists with H3K27me3 in pluripotent and differentiated cells. However, we find that the functioning...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952858/ https://www.ncbi.nlm.nih.gov/pubmed/24430871 http://dx.doi.org/10.1091/mbc.E13-10-0628 |