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Elucidating the ensemble of functionally-relevant transitions in protein systems with a robotics-inspired method

BACKGROUND: Many proteins tune their biological function by transitioning between different functional states, effectively acting as dynamic molecular machines. Detailed structural characterization of transition trajectories is central to understanding the relationship between protein dynamics and f...

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Detalles Bibliográficos
Autores principales: Molloy, Kevin, Shehu, Amarda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952944/
https://www.ncbi.nlm.nih.gov/pubmed/24565158
http://dx.doi.org/10.1186/1472-6807-13-S1-S8