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Elucidating the ensemble of functionally-relevant transitions in protein systems with a robotics-inspired method
BACKGROUND: Many proteins tune their biological function by transitioning between different functional states, effectively acting as dynamic molecular machines. Detailed structural characterization of transition trajectories is central to understanding the relationship between protein dynamics and f...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952944/ https://www.ncbi.nlm.nih.gov/pubmed/24565158 http://dx.doi.org/10.1186/1472-6807-13-S1-S8 |