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Bone Mineral Density Changes among HIV-Uninfected Young Adults in a Randomised Trial of Pre-Exposure Prophylaxis with Tenofovir-Emtricitabine or Placebo in Botswana

BACKGROUND: Tenofovir-emtricitabine (TDF-FTC) pre-exposure prophylaxis (PrEP) has been found to be effective for prevention of HIV infection in several clinical trials. Two studies of TDF PrEP among men who have sex with men showed slight bone mineral density (BMD) loss. We investigated the effect o...

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Detalles Bibliográficos
Autores principales: Kasonde, Michael, Niska, Richard W., Rose, Charles, Henderson, Faith L., Segolodi, Tebogo M., Turner, Kyle, Smith, Dawn K., Thigpen, Michael C., Paxton, Lynn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953113/
https://www.ncbi.nlm.nih.gov/pubmed/24625530
http://dx.doi.org/10.1371/journal.pone.0090111