Purine Analog-Like Properties of Bendamustine Underlie Rapid Activation of DNA Damage Response and Synergistic Effects with Pyrimidine Analogues in Lymphoid Malignancies

Bendamustine has shown considerable clinical activity against indolent lymphoid malignancies as a single agent or in combination with rituximab, but combination with additional anti-cancer drugs may be required for refractory and/or relapsed cases as well as other intractable tumors. In this study,...

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Detalles Bibliográficos
Autores principales: Hiraoka, Nobuya, Kikuchi, Jiro, Yamauchi, Takahiro, Koyama, Daisuke, Wada, Taeko, Uesawa, Mitsuyo, Akutsu, Miyuki, Mori, Shigehisa, Nakamura, Yuichi, Ueda, Takanori, Kano, Yasuhiko, Furukawa, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953125/
https://www.ncbi.nlm.nih.gov/pubmed/24626203
http://dx.doi.org/10.1371/journal.pone.0090675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953125/
https://www.ncbi.nlm.nih.gov/pubmed/24626203
http://dx.doi.org/10.1371/journal.pone.0090675

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