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A population-based evolutionary search approach to the multiple minima problem in de novo protein structure prediction
BACKGROUND: Elucidating the native structure of a protein molecule from its sequence of amino acids, a problem known as de novo structure prediction, is a long standing challenge in computational structural biology. Difficulties in silico arise due to the high dimensionality of the protein conformat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953177/ https://www.ncbi.nlm.nih.gov/pubmed/24565020 http://dx.doi.org/10.1186/1472-6807-13-S1-S4 |