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NOD2/RICK-Dependent β-Defensin 2 Regulation Is Protective for Nontypeable Haemophilus influenzae-Induced Middle Ear Infection

Middle ear infection, otitis media (OM), is clinically important due to the high incidence in children and its impact on the development of language and motor coordination. Previously, we have demonstrated that the human middle ear epithelial cells up-regulate β-defensin 2, a model innate immune mol...

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Detalles Bibliográficos
Autores principales: Woo, Jeong-Im, Oh, Sejo, Webster, Paul, Lee, Yoo Jin, Lim, David J., Moon, Sung K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953203/
https://www.ncbi.nlm.nih.gov/pubmed/24625812
http://dx.doi.org/10.1371/journal.pone.0090933