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Modeling protein conformational transitions by a combination of coarse-grained normal mode analysis and robotics-inspired methods
BACKGROUND: Obtaining atomic-scale information about large-amplitude conformational transitions in proteins is a challenging problem for both experimental and computational methods. Such information is, however, important for understanding the mechanisms of interaction of many proteins. METHODS: Thi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953241/ https://www.ncbi.nlm.nih.gov/pubmed/24564964 http://dx.doi.org/10.1186/1472-6807-13-S1-S2 |