Cargando…

Modeling protein conformational transitions by a combination of coarse-grained normal mode analysis and robotics-inspired methods

BACKGROUND: Obtaining atomic-scale information about large-amplitude conformational transitions in proteins is a challenging problem for both experimental and computational methods. Such information is, however, important for understanding the mechanisms of interaction of many proteins. METHODS: Thi...

Descripción completa

Detalles Bibliográficos
Autores principales: Al-Bluwi, Ibrahim, Vaisset, Marc, Siméon, Thierry, Cortés, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953241/
https://www.ncbi.nlm.nih.gov/pubmed/24564964
http://dx.doi.org/10.1186/1472-6807-13-S1-S2