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Isotopic decay of urinary or plasma 3-methylhistidine as a potential biomarker of pathologic skeletal muscle loss

BACKGROUND: Skeletal muscle loss accompanying aging or cancer is associated with reduced physical function and predicts morbidity and mortality. 3-Methylhistidine (3MH) has been proposed as a biomarker of myofibrillar proteolysis, which may contribute to skeletal muscle loss. METHODS: We hypothesize...

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Detalles Bibliográficos
Autores principales: Sheffield-Moore, M., Dillon, E. L., Randolph, K. M., Casperson, S. L., White, G. R., Jennings, K., Rathmacher, J., Schuette, S., Janghorbani, M., Urban, R. J., Hoang, V., Willis, M., Durham, W. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953321/
https://www.ncbi.nlm.nih.gov/pubmed/24009031
http://dx.doi.org/10.1007/s13539-013-0117-7