Hydrodynamic Delivery of Cre Protein to Lineage-Mark or Time-Stamp Mouse Hepatocytes In situ

Cre-responsive fluorescent marker alleles are powerful tools for cell lineage tracing in mice; however their utility is limited by regulation of Cre activity. When targeting hepatocytes, hydrodynamic delivery of a Cre-expression plasmid can convert Cre-responsive alleles without inducing the intrace...

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Detalles Bibliográficos
Autores principales: Sonsteng, Katherine M., Prigge, Justin R., Talago, Emily A., June, Ronald K., Schmidt, Edward E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953374/
https://www.ncbi.nlm.nih.gov/pubmed/24626158
http://dx.doi.org/10.1371/journal.pone.0091219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953374/
https://www.ncbi.nlm.nih.gov/pubmed/24626158
http://dx.doi.org/10.1371/journal.pone.0091219

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