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A polarized Ca(2+), diacylglycerol, and STIM1 signaling system regulates directed cell migration

Ca(2+) signals control cell migration by regulating forward movement and cell adhesion. However, it is not well understood how Ca(2+)-regulatory proteins and second messengers are spatially organized in migrating cells. Here we show that receptor tyrosine kinase and phospholipase C signaling are res...

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Detalles Bibliográficos
Autores principales: Tsai, Feng-Chiao, Seki, Akiko, Yang, Hee Won, Hayer, Arnold, Carrasco, Silvia, Malmersjö, Seth, Meyer, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953390/
https://www.ncbi.nlm.nih.gov/pubmed/24463606
http://dx.doi.org/10.1038/ncb2906