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VE-Cadherin Cleavage by LasB Protease from Pseudomonas aeruginosa Facilitates Type III Secretion System Toxicity in Endothelial Cells

Infection of the vascular system by Pseudomonas aeruginosa (Pa) occurs during bacterial dissemination in the body or in blood-borne infections. Type 3 secretion system (T3SS) toxins from Pa induce a massive retraction when injected into endothelial cells. Here, we addressed the role of type 2 secret...

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Detalles Bibliográficos
Autores principales: Golovkine, Guillaume, Faudry, Eric, Bouillot, Stéphanie, Voulhoux, Romé, Attrée, Ina, Huber, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953407/
https://www.ncbi.nlm.nih.gov/pubmed/24626230
http://dx.doi.org/10.1371/journal.ppat.1003939