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Inflammasome Sensor NLRP1 Controls Rat Macrophage Susceptibility to Toxoplasma gondii

Toxoplasma gondii is an intracellular parasite that infects a wide range of warm-blooded species. Rats vary in their susceptibility to this parasite. The Toxo1 locus conferring Toxoplasma resistance in rats was previously mapped to a region of chromosome 10 containing Nlrp1. This gene encodes an inf...

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Detalles Bibliográficos
Autores principales: Cirelli, Kimberly M., Gorfu, Gezahegn, Hassan, Musa A., Printz, Morton, Crown, Devorah, Leppla, Stephen H., Grigg, Michael E., Saeij, Jeroen P. J., Moayeri, Mahtab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953412/
https://www.ncbi.nlm.nih.gov/pubmed/24626226
http://dx.doi.org/10.1371/journal.ppat.1003927