DNA and Protein Co-Immunization Improves the Magnitude and Longevity of Humoral Immune Responses in Macaques

We tested the concept of combining DNA with protein to improve anti-HIV Env systemic and mucosal humoral immune responses. Rhesus macaques were vaccinated with DNA, DNA&protein co-immunization or DNA prime followed by protein boost, and the magnitude and mucosal dissemination of the antibody res...

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Detalles Bibliográficos
Autores principales: Jalah, Rashmi, Kulkarni, Viraj, Patel, Vainav, Rosati, Margherita, Alicea, Candido, Bear, Jenifer, Yu, Lei, Guan, Yongjun, Shen, Xiaoying, Tomaras, Georgia D., LaBranche, Celia, Montefiori, David C., Prattipati, Rajasekhar, Pinter, Abraham, Bess, Julian, Lifson, Jeffrey D., Reed, Steven G., Sardesai, Niranjan Y., Venzon, David J., Valentin, Antonio, Pavlakis, George N., Felber, Barbara K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953433/
https://www.ncbi.nlm.nih.gov/pubmed/24626482
http://dx.doi.org/10.1371/journal.pone.0091550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953433/
https://www.ncbi.nlm.nih.gov/pubmed/24626482
http://dx.doi.org/10.1371/journal.pone.0091550

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