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Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes
Phenotypic screening is making a comeback in drug discovery as the maturation of chemical proteomics methods has facilitated target identification for bioactive small molecules. A limitation of these approaches is that time-consuming genetic methods or other means is often required to determine the...
| Autores principales: | , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953460/ https://www.ncbi.nlm.nih.gov/pubmed/24362705 http://dx.doi.org/10.1038/nchembio.1429 |