BEX1 Promotes Imatinib-Induced Apoptosis by Binding to and Antagonizing BCL-2

An enhanced anti-apoptotic capacity of tumor cells plays an important role in the process of breakpoint cluster region/Abelson tyrosine kinase gene (BCR/ABL)-independent imatinib resistance. We have previously demonstrated that brain expressed X-linked 1 (BEX1) was silenced in secondary imatinib-res...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiao, Qian, Hu, Yeting, Liu, Yue, Wang, Zhanhuai, Geng, Haitao, Hu, Lifeng, Xu, Dengyong, Wang, Ke, Zheng, Lei, Zheng, Shu, Ding, Kefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953594/
https://www.ncbi.nlm.nih.gov/pubmed/24626299
http://dx.doi.org/10.1371/journal.pone.0091782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953594/
https://www.ncbi.nlm.nih.gov/pubmed/24626299
http://dx.doi.org/10.1371/journal.pone.0091782

Ejemplares similares