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BEX1 Promotes Imatinib-Induced Apoptosis by Binding to and Antagonizing BCL-2
An enhanced anti-apoptotic capacity of tumor cells plays an important role in the process of breakpoint cluster region/Abelson tyrosine kinase gene (BCR/ABL)-independent imatinib resistance. We have previously demonstrated that brain expressed X-linked 1 (BEX1) was silenced in secondary imatinib-res...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953594/ https://www.ncbi.nlm.nih.gov/pubmed/24626299 http://dx.doi.org/10.1371/journal.pone.0091782 |