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Overexpression of WRAP53 Is Associated with Development and Progression of Esophageal Squamous Cell Carcinoma

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is a highly aggressive cancer whose underlying molecular mechanisms are poorly understood. The natural antisense transcript (NAT) WRAP53 regulates p53 expression and WRAP53 protein is a component of telomerase. NATs play key roles in carcinogenes...

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Detalles Bibliográficos
Autores principales: Rao, Xuguang, Huang, Daofu, Sui, Xuxia, Liu, Gefei, Song, Xuhong, Xie, Jinglian, Huang, Dongyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953598/
https://www.ncbi.nlm.nih.gov/pubmed/24626331
http://dx.doi.org/10.1371/journal.pone.0091670