Point mutation of the xylose reductase (XR) gene reduces xylitol accumulation and increases citric acid production in Aspergillus carbonarius

Aspergillus carbonarius accumulates xylitol when it grows on d-xylose. In fungi, d-xylose is reduced to xylitol by the NAD(P)H-dependent xylose reductase (XR). Xylitol is then further oxidized by the NAD(+)-dependent xylitol dehydrogenase (XDH). The cofactor impairment between the XR and XDH can lea...

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Detalles Bibliográficos
Autores principales: Weyda, István, Lübeck, Mette, Ahring, Birgitte K., Lübeck, Peter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Metabolic Engineering and Synthetic Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953602/
https://www.ncbi.nlm.nih.gov/pubmed/24570325
http://dx.doi.org/10.1007/s10295-014-1415-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953602/
https://www.ncbi.nlm.nih.gov/pubmed/24570325
http://dx.doi.org/10.1007/s10295-014-1415-6

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