The deleterious mutation load is insensitive to recent population history

Human populations have undergone dramatic changes in population size in the past 100,000 years, including recent rapid growth. How these demographic events have affected the burden of deleterious mutations in individuals and the frequencies of disease mutations in populations remains unclear. We use...

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Detalles Bibliográficos
Autores principales: Simons, Yuval B., Turchin, Michael C., Pritchard, Jonathan K., Sella, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953611/
https://www.ncbi.nlm.nih.gov/pubmed/24509481
http://dx.doi.org/10.1038/ng.2896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953611/
https://www.ncbi.nlm.nih.gov/pubmed/24509481
http://dx.doi.org/10.1038/ng.2896

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