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4-Hydroxy-2-nonenal Induces Apoptosis by Inhibiting AKT Signaling in Human Osteosarcoma Cells

The onset of lipid peroxidation within cellular membranes is associated with changes in their physiochemical properties and enzymatic dysfunction of the membrane environment. There are increasing bodies of evidence indicating that aldehydic molecules generated endogenously during the process of lipi...

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Detalles Bibliográficos
Autores principales: Ji, Guang-rong, Yu, Nai-chun, Xue, Xiang, Li, Zong-guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953651/
https://www.ncbi.nlm.nih.gov/pubmed/24711740
http://dx.doi.org/10.1155/2014/873525