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Effects of Various Antiepileptics Used to Alleviate Neuropathic Pain on Compound Action Potential in Frog Sciatic Nerves: Comparison with Those of Local Anesthetics

Antiepileptics used for treating neuropathic pain have various actions including voltage-gated Na(+) and Ca(2+) channels, glutamate-receptor inhibition, and GABA(A)-receptor activation, while local anesthetics are also used to alleviate the pain. It has not been fully examined yet how nerve conducti...

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Detalles Bibliográficos
Autores principales: Uemura, Yuhei, Fujita, Tsugumi, Ohtsubo, Sena, Hirakawa, Naomi, Sakaguchi, Yoshiro, Kumamoto, Eiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953671/
https://www.ncbi.nlm.nih.gov/pubmed/24707490
http://dx.doi.org/10.1155/2014/540238