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Mechanisms regulating neuronal excitability and seizure development following mTOR pathway hyperactivation
The phosphatidylinositol-3-kinase/phosphatase and tensin homolog (PTEN)-mammalian target of rapamycin (mTOR) pathway regulates a variety of neuronal functions, including cell proliferation, survival, growth, and plasticity. Dysregulation of the pathway is implicated in the development of both geneti...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953715/ https://www.ncbi.nlm.nih.gov/pubmed/24672426 http://dx.doi.org/10.3389/fnmol.2014.00018 |