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Mechanisms regulating neuronal excitability and seizure development following mTOR pathway hyperactivation

The phosphatidylinositol-3-kinase/phosphatase and tensin homolog (PTEN)-mammalian target of rapamycin (mTOR) pathway regulates a variety of neuronal functions, including cell proliferation, survival, growth, and plasticity. Dysregulation of the pathway is implicated in the development of both geneti...

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Detalles Bibliográficos
Autores principales: LaSarge, Candi L., Danzer, Steve C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953715/
https://www.ncbi.nlm.nih.gov/pubmed/24672426
http://dx.doi.org/10.3389/fnmol.2014.00018