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Origin and evolution of the Peptidyl Transferase Center from proto-tRNAs

We tested the hypothesis of Tamura (2011) [3] that molecules of tRNA gave origin to ribosomes, particularly to the Peptidyl Transferase Center (PTC) of the 23S ribosomal RNA. We reconstructed the ancestral sequences from all types of tRNA and compared them in their sequences with the current PTC of...

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Detalles Bibliográficos
Autores principales: Farias, Sávio T., Rêgo, Thais G., José, Marco V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953717/
https://www.ncbi.nlm.nih.gov/pubmed/24649398
http://dx.doi.org/10.1016/j.fob.2014.01.010