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Anti-cancer small molecule JP-8g exhibits potent in vivo anti-inflammatory activity

Spirooxindoles are a class of compounds with diverse biological activity. Previously, we identified a series of spirooxindole-pyranopyrimidine compounds that exhibited broad-spectrum anti-cancer activity. In this study, we evaluated one of these compounds, JP-8g, on mouse models and found that it sh...

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Detalles Bibliográficos
Autores principales: Sun, Yulong, Liu, Jia, Sun, Tao, Zhang, Xiaoyuan, Yao, Jia, Kai, Ming, Jiang, Xianxing, Wang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953725/
https://www.ncbi.nlm.nih.gov/pubmed/24626153
http://dx.doi.org/10.1038/srep04372