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The total burden of rare, non-synonymous exome genetic variants is not associated with childhood or late-life cognitive ability
Human cognitive ability shows consistent, positive associations with fitness components across the life-course. Underlying genetic variation should therefore be depleted by selection, which is not observed. Genetic variation in general cognitive ability (intelligence) could be maintained by a mutati...
Autores principales: | Marioni, Riccardo E., Penke, Lars, Davies, Gail, Huffman, Jennifer E., Hayward, Caroline, Deary, Ian J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953855/ https://www.ncbi.nlm.nih.gov/pubmed/24573858 http://dx.doi.org/10.1098/rspb.2014.0117 |
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