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Bisphosphonate-Anchored PEGylation and Radiolabeling of Superparamagnetic Iron Oxide: Long-Circulating Nanoparticles for in Vivo Multimodal (T1 MRI-SPECT) Imaging

[Image: see text] The efficient delivery of nanomaterials to specific targets for in vivo biomedical imaging is hindered by rapid sequestration by the reticuloendothelial system (RES) and consequent short circulation times. To overcome these two problems, we have prepared a new stealth PEG polymer c...

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Detalles Bibliográficos
Autores principales: Sandiford, Lydia, Phinikaridou, Alkystis, Protti, Andrea, Meszaros, Levente K., Cui, Xianjin, Yan, Yong, Frodsham, George, Williamson, Peter A., Gaddum, Nicholas, Botnar, René M., Blower, Philip J., Green, Mark A., de Rosales, Rafael T. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953894/
https://www.ncbi.nlm.nih.gov/pubmed/23194247
http://dx.doi.org/10.1021/nn3046055