Anti-epidermal growth factor receptor monoclonal antibody-based therapy for metastatic colorectal cancer: a meta-analysis of the effect of PIK3CA mutations in KRAS wild-type patients

INTRODUCTION: We conducted a meta-analysis to dissect the association between PIK3CA mutations (exon 9 and exon 20) and resistance to anti-epidermal growth factor receptor (EGFR) monoclonal antibodies (MoAbs) in KRAS wild-type metastatic colorectal cancer (mCRC) patients. MATERIAL AND METHODS: In 11...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Lulu, Liu, Zhenfang, Deng, Donghong, Tan, Aihua, Liao, Ming, Mo, Zengnan, Yang, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2014
Materias:
Systematic review/Meta-analysis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953972/
https://www.ncbi.nlm.nih.gov/pubmed/24701207
http://dx.doi.org/10.5114/aoms.2014.40728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953972/
https://www.ncbi.nlm.nih.gov/pubmed/24701207
http://dx.doi.org/10.5114/aoms.2014.40728

Ejemplares similares