A high-throughput approach for measuring temporal changes in the interactome

Interactomes are often measured using affinity purification-mass spectrometry (AP-MS) or yeast two-hybrid approaches but these lack stoichiometric or temporal information. We combine quantitative proteomics and size exclusion chromatography to map 291 coeluting complexes. This method allows mapping...

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Detalles Bibliográficos
Autores principales: Kristensen, Anders R., Gsponer, Joerg, Foster, Leonard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954081/
https://www.ncbi.nlm.nih.gov/pubmed/22863883
http://dx.doi.org/10.1038/nmeth.2131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954081/
https://www.ncbi.nlm.nih.gov/pubmed/22863883
http://dx.doi.org/10.1038/nmeth.2131

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