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Tyrosine/Cysteine Cluster Sensitizing Human γD-Crystallin to Ultraviolet Radiation-Induced Photoaggregation in Vitro

[Image: see text] Ultraviolet radiation (UVR) exposure is a major risk factor for age-related cataract, a protein-aggregation disease of the human lens often involving the major proteins of the lens, the crystallins. γD-Crystallin (HγD-Crys) is abundant in the nucleus of the human lens, and its fold...

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Detalles Bibliográficos
Autores principales: Schafheimer, Nathaniel, Wang, Zhen, Schey, Kevin, King, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954642/
https://www.ncbi.nlm.nih.gov/pubmed/24410332
http://dx.doi.org/10.1021/bi401397g