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Xmrk, Kras and Myc Transgenic Zebrafish Liver Cancer Models Share Molecular Signatures with Subsets of Human Hepatocellular Carcinoma

Previously three oncogene transgenic zebrafish lines with inducible expression of xmrk, kras or Myc in the liver have been generated and these transgenic lines develop oncogene-addicted liver tumors upon chemical induction. In the current study, comparative transcriptomic approaches were used to exa...

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Detalles Bibliográficos
Autores principales: Zheng, Weiling, Li, Zhen, Nguyen, Anh Tuan, Li, Caixia, Emelyanov, Alexander, Gong, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954698/
https://www.ncbi.nlm.nih.gov/pubmed/24633177
http://dx.doi.org/10.1371/journal.pone.0091179