Asymmetric Synthesis of 2-Substituted Oxetan-3-ones via Metalated SAMP/RAMP Hydrazones

[Image: see text] 2-Substituted oxetan-3-ones can be prepared in good yields and enantioselectivities (up to 84% ee) by the metalation of the SAMP/RAMP hydrazones of oxetan-3-one, followed by reaction with a range of electrophiles that include alkyl, allyl, and benzyl halides. Additionally, both chi...

Descripción completa

Detalles Bibliográficos
Autores principales: Geden, Joanna V., Beasley, Benjamin O., Clarkson, Guy J., Shipman, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954718/
https://www.ncbi.nlm.nih.gov/pubmed/24152298
http://dx.doi.org/10.1021/jo4020485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954718/
https://www.ncbi.nlm.nih.gov/pubmed/24152298
http://dx.doi.org/10.1021/jo4020485

Ejemplares similares