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Development of Selective Inhibitors for Aldehyde Dehydrogenases Based on Substituted Indole-2,3-diones

[Image: see text] Aldehyde dehydrogenases (ALDH) participate in multiple metabolic pathways and have been indicated to play a role in several cancerous disease states. Our laboratory is interested in developing novel and selective ALDH inhibitors. We looked to further work recently published by deve...

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Detalles Bibliográficos
Autores principales: Kimble-Hill, Ann C., Parajuli, Bibek, Chen, Che-Hong, Mochly-Rosen, Daria, Hurley, Thomas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954746/
https://www.ncbi.nlm.nih.gov/pubmed/24444054
http://dx.doi.org/10.1021/jm401377v