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Development of Selective Inhibitors for Aldehyde Dehydrogenases Based on Substituted Indole-2,3-diones
[Image: see text] Aldehyde dehydrogenases (ALDH) participate in multiple metabolic pathways and have been indicated to play a role in several cancerous disease states. Our laboratory is interested in developing novel and selective ALDH inhibitors. We looked to further work recently published by deve...
Autores principales: | Kimble-Hill, Ann C., Parajuli, Bibek, Chen, Che-Hong, Mochly-Rosen, Daria, Hurley, Thomas D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954746/ https://www.ncbi.nlm.nih.gov/pubmed/24444054 http://dx.doi.org/10.1021/jm401377v |
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