High Content Image Analysis Identifies Novel Regulators of Synaptogenesis in a High-Throughput RNAi Screen of Primary Neurons

The formation of synapses, the specialized points of chemical communication between neurons, is a highly regulated developmental process fundamental to establishing normal brain circuitry. Perturbations of synapse formation and function causally contribute to human developmental and degenerative neu...

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Detalles Bibliográficos
Autores principales: Nieland, Thomas J. F., Logan, David J., Saulnier, Jessica, Lam, Daniel, Johnson, Caroline, Root, David E., Carpenter, Anne E., Sabatini, Bernardo L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954765/
https://www.ncbi.nlm.nih.gov/pubmed/24633176
http://dx.doi.org/10.1371/journal.pone.0091744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954765/
https://www.ncbi.nlm.nih.gov/pubmed/24633176
http://dx.doi.org/10.1371/journal.pone.0091744

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