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The Focal Adhesion-Localized CdGAP Regulates Matrix Rigidity Sensing and Durotaxis
Motile cells are capable of sensing the stiffness of the surrounding extracellular matrix through integrin-mediated focal adhesions and migrate towards regions of higher rigidity in a process known as durotaxis. Durotaxis plays an important role in normal development and disease progression, includi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954768/ https://www.ncbi.nlm.nih.gov/pubmed/24632816 http://dx.doi.org/10.1371/journal.pone.0091815 |