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Nuclear Export of L-Periaxin, Mediated by Its Nuclear Export Signal in the PDZ Domain

Myelinating Schwann cells specifically express L-periaxin (L-PRX) in the mammalian peripheral nervous system. Several loss-of-function mutations in periaxin have been described and linked to autosomal recessive Dejerine Sottas neuropathy and to demyelinating Charcot-Marie-Tooth disease. The localiza...

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Detalles Bibliográficos
Autores principales: Shi, Yawei, Zhang, Lei, Yang, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954830/
https://www.ncbi.nlm.nih.gov/pubmed/24633211
http://dx.doi.org/10.1371/journal.pone.0091953