Structural Characterization of Two Metastable ATP-Bound States of P-Glycoprotein

ATP Binding Cassette (ABC) transporters couple the binding and hydrolysis of ATP to the transport of substrate molecules across the membrane. The mechanism by which ATP binding and/or hydrolysis drives the conformational changes associated with substrate transport has not yet been characterized full...

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Detalles Bibliográficos
Autores principales: O’Mara, Megan L., Mark, Alan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954865/
https://www.ncbi.nlm.nih.gov/pubmed/24632881
http://dx.doi.org/10.1371/journal.pone.0091916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954865/
https://www.ncbi.nlm.nih.gov/pubmed/24632881
http://dx.doi.org/10.1371/journal.pone.0091916

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