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Combined Effects of Genetic Variants of the PTEN, AKT1, MDM2 and p53 Genes on the Risk of Nasopharyngeal Carcinoma

Phosphatase and tensin homolog (PTEN), v-akt murine thymoma viral oncogene homolog 1 (AKT1), mouse double minute 2 (MDM2) and p53 play important roles in the development of cancer. We examined whether the single nucleotide polymorphisms (SNPs) in the PTEN, AKT1, MDM2 and p53 genes were related to th...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoai, Chen, Xi, Zhai, Yun, Cui, Ying, Cao, Pengbo, Zhang, Hongxing, Wu, Zhihao, Li, Peiyao, Yu, Lixa, Xia, Xia, He, Fuchu, Zhou, Gangqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954877/
https://www.ncbi.nlm.nih.gov/pubmed/24632578
http://dx.doi.org/10.1371/journal.pone.0092135